Sergio E. Baranzini is Distinguished Professor of Neurology at the University of California San Francisco (UCSF). He earned his Ph.D. in human molecular genetics (1997) from the University of Buenos Aires, Argentina. His lab at UCSF uses a multi-disciplinary approach to science and it is composed by experimental and computational researchers. Dr. Baranzini leads the iMSMS, an international consortium to study the effect of bacterial populations (microbiota) on MS susceptibility and progression. In addition, he is the principal investigator of SPOKE, a large multi-disciplinary bioinformatics approach to gather, integrate and analyze all biomedical data, currently supported by NIH and NSF.

2021 Talk: SPOKE: a biomedical open knowledge graph

SPOKE is a biomedical knowledge graph containing factual data on various biomedical fields including genetics, molecular biology, physiology, metabolomics, pharmacology and clinical medicine. SPOKE can be used to repurpose medications, predict patient outcomes, and accelerate drug development, among other uses.